Hematology · Patient education
Lymphoma
Lymphoma is a cancer that starts in lymphocytes, a type of white blood cell that helps fight infection. It often shows up as swollen lymph nodes that don't go away. There are many types, and treatment has improved a great deal. Your care team works with oncology specialists to guide you through each step.
Lymphocytes live in your lymph nodes, spleen, bone marrow and other parts of the body. In lymphoma, some of these cells grow out of control and can build up in lymph nodes or organs.
Lymphoma is different from leukemia, which usually starts in the bone marrow and blood, though the two can overlap.
Non-Hodgkin lymphoma is one of the more common cancers in the United States. Hodgkin lymphoma is less common. Lymphoma can happen at any age, but some types are more common in young adults and others in older adults.
- Hodgkin lymphoma: has a specific kind of abnormal cell seen under a microscope.
- Non-Hodgkin lymphoma: a large group of many different types.
- Slow-growing (indolent) lymphomas: may grow over years and sometimes only need watching at first.
- Fast-growing (aggressive) lymphomas: need treatment soon after diagnosis.
- Your specialist will name your exact type, because treatment depends on it.
Most people with lymphoma have no clear cause. Things that can raise the risk include:
- Getting older (for many types)
- A weakened immune system, such as from HIV, an organ transplant or certain medicines
- Some autoimmune diseases
- Some infections, such as Epstein-Barr virus or H. pylori
- A family history of lymphoma
- Painless swollen lymph nodes in the neck, armpit or groin that don't go away
- Fevers without a clear cause
- Drenching night sweats
- Weight loss without trying
- Feeling very tired
- Itching
- Cough, chest pressure or trouble breathing, or a full feeling in the belly
- At your visit, your provider feels for swollen lymph nodes and checks your belly for an enlarged spleen or liver. Many swollen nodes are caused by infections, not cancer.
Lymphoma is confirmed with a biopsy, where a sample of a lymph node or tissue is checked under a microscope. This is done by a specialist.
Lab tests your provider may order include: a complete blood count (CBC) with differential, a comprehensive metabolic panel, LDH, and sometimes tests for HIV and hepatitis.
Scans such as CT or PET scans, and sometimes a bone marrow test, help show where the lymphoma is. We don't do imaging or biopsies at our office; we refer you to trusted partners and review the results with you.
- Treatment is planned by an oncology or hematology specialist and depends on the type and stage.
- Options may include watchful waiting for some slow-growing types, chemotherapy, immunotherapy, targeted medicines, radiation, or stem cell transplant.
- Eat well, stay as active as you can, and rest when you need to.
- Tell your care team about side effects early; many can be eased.
- Emotional support matters. Support groups, counseling and loved ones can help.
Many types of lymphoma respond well to treatment, and some can be cured. Others are managed over time like a long-term condition.
Every person's situation is different. Your specialist is the best person to talk with about what to expect for your type.
Call 911 for severe trouble breathing, chest pain, confusion, or fainting.
If you are getting treatment and have a fever of 100.4°F (38°C) or higher, call your oncology team or us at (818) 660-2977 right away. If you can't reach anyone, you need emergency care or 911. Fevers during treatment can be serious.
Call us at (818) 660-2977 for: a swollen lymph node that lasts more than 2 to 3 weeks, night sweats, unexplained fevers or weight loss, or new swelling in your face, neck or arms.
Your primary care team at Moaddel Medical checks symptoms, orders labs, and refers you to our hematology and oncology partner, Wellness Oncology & Hematology (Dr. Omid Shaye, Dr. Ashkan Lashkari and Dr. Christopher Ho; wellnessoncology.com), for biopsy, scans and treatment.
We stay involved: we help coordinate your care, manage your other health conditions, and answer questions along the way.
We're at 7230 Medical Center Dr, Suite 100, West Hills, CA 91307.
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Start with a visit at Moaddel Medical, 7230 Medical Center Dr, Suite 100, West Hills, CA 91307. We'll review your concerns and plan next steps together.
Education only. This information is for general education and is not medical advice. It does not replace a visit with a qualified health care provider. If you think you may have a medical emergency, call 911 right away.
Sources
- MedlinePlus: Lymphoma (opens in a new tab)
- MedlinePlus: Hodgkin Lymphoma (opens in a new tab)
- Wellness Oncology & Hematology (our hematology/oncology partner, West Hills) (opens in a new tab)
- National Cancer Institute: Lymphoma—Patient Version (opens in a new tab)
Last reviewed: Pending medical review